DESIGN OF AZITHROMYCIN LOADED EUDRAGIT RL 100 NANOPARTICLES WITH EXTENDED ANTIBACTERIAL EFFECT

Preparation and Characterization of Nitrendipine- loaded Eudragit RL 100 Microspheres Prepared by an Emulsion-Solvent Evaporation Method

Purpose: The aim of the work was to prepare nitrendipne-loaded Eudragit RL 100 microspheres to achieve sustained release nitrendipine. Method: Nitrendipne-loaded Eudragit RL 100 microspheres were prepared by an emulsion-solvent evaporation method using ethanol/liquid paraffin system. The resultant microspheres were evaluated for average particle size, drug loading, in vitro drug release and rel...

Evaluation of Antibacterial Effect of Curcumin Loaded Chitosan Nanoparticles

  Background & Objective: Nanomedicine delivery systems are known as potent therapeutictools. In addition to possessing an effective agent of turmeric, Curcumin shows antibacterial properties as well. Curcumin is not water-soluble and it can be solved in water via nanotechnology-base methods. Chitosan is a natural and biodegradable substance that is utilized for the Production of Nanoparticles ...

antibacterial evaluation of azithromycin nanoparticles

Design of eudragit RL nanoparticles by nanoemulsion method as carriers for ophthalmic drug delivery of ketotifen fumarate

Objective(s): Ketotifen fumarate (KF) is a selective and noncompetitive histamine antagonist (H1-receptor) that is used topically in the treatment of allergic conditions of rhinitis and conjunctivitis. The aim of this study was to formulate and improve an ophthalmic delivery system of KF.Ocular nanoparticles were prepared with the objective of reducing the frequency of administration and obtain...

Ranitidine Hydrochloride-loaded Ethyl Cellulose and Eudragit RS 100 Buoyant Microspheres: Effect of pH Modifiers

A floating type of dosage form of ranitidine hydrochloride in the form of microspheres capable of floating on simulated gastric fluid was prepared by solvent evaporation technique. Microspheres prepared with ethyl cellulose, Eudragit(®) RS100 alone or in combination were evaluated for percent yield, drug entrapment, percent buoyancy and drug release and the results demonstrated satisfactory per...